Scalable simulation of stochastic multicellular systems

In multicellular systems, cells of different types interact in various ways, both mechanically and chemically, to regulate complex processes. There is a large computational gap between detailed models of sub-cellular, molecular processes in single cells, and models of multicellular systems comprising of large numbers of interacting cells such as bacterial colonies, tissue and tumors. In […]

Intelligent model exploration

The integration between on the one hand data, modeling and algorithms, and on the other hand the specification, coordination and execution of large scale and data-intensive computational experiments poses a fundamental problem in all scientific disciplines relying on modeling and simulation. Today it is largely left to the modeler or engineer to manually tune models […]

StochSS: Stochastic Simulation Service

StochSS is an integrated development environment (IDE) for discrete stochastic biochemical simulations. Users make use of a graphical user interface (GUI) to define their problem, including its domain (geometry, volume), molecular interactions (stoichiometry, rate constants), and simulation goals (single trajectory, histogram, probabilities of rare events). The platform transparently executes model workflows using local resources (laptops, […]

Multiscale simulations of chemical kinetics

Life spans in size from small organisms consisting of single cells to complex organisms built up of billions of cells. Even the single-cell organisms are challenging to fully understand and study—their function is dependent on a rich set of reaction networks. Important molecules inside a cell may exist in only a few copies, and that […]

Postdoc in Scientific Computing/Applied Cloud Computing

We are looking for a talented individual to join our efforts on creating smart and scalable cloud services to support simulation-driven scientific discovery via large-scale computational experiments such as parameter sweeps. This is a classic and very important problem that we will approach in new ways, leveraging recent advances in cloud computing, data-intensive computing and machine […]

Göran Gustafsson prize

Last week brought some great news. I am awarded the Göran Gustafsson Prize 2016 from the Gustafsson Foundation (KTH/UU). In the proposed project titled Smart Services for Scientific Discovery we will look into new and more productive ways to combine simulation software and cloud computing infrastructure to build intelligent applications for e.g. exploring an underlying model’s essential […]

At Isaac Newton Institute

I will be spending Feb 15-March 17 at the Isaac Newton Institute, Cambride, UK, for a program on Stochastic Dynamical Systems in Biology: Numerical Methods and Applications. Big thanks to the organizers,Radek Erban (Oxford), David Holcman (ENS – Paris), Samuel Isaacson (Boston) and Konstantinos Zygalakis (Southampton) for organizing this amazing opportunity to gather many creative people in […]

Open Posititions: up to two PhD students

(Call for applications is closed. ) We are expanding the group with up to two PhD students in the areas of Applied Mathematics and Applied Cloud Computing: CIM, the Center for Interdisciplinary Mathematics are hiring students.  We are, in collaboration with the Spjuth lab offering the project, Smart and Efficient Scientific Software for Exploration of Vast Amounts […]